Most Recent Articles: BMC Medical Genomics Most Recent Articles: BMC Medical Genomics
- Genomic profiling and expanded use of targeted anticancer drugs in solid cancers with exhausted evidence-based treatment options (PRECODE): study protocol of a prospective, non-randomized, cohort studypor Karin Holmskov Hansen, Maria Bibi Lyng, Annette Raskov Kodahl, Jon Thor Asmussen, Arman Arshad, Henrik Petersen, Lotte Krogh, Sidse Ehmsen, Thomas Kielsgaard Kristensen and Henrik J. Ditzel on noviembre 21, 2024 at 12:00 am
Genomic profiling of advanced solid cancer in patients with no further evidence based standard treatment options is a novel approach to identify potential experimental treatment options based on specific genom...
- Private detection of relatives in forensic genomics using homomorphic encryptionpor Fillipe D. M. de Souza, Hubert de Lassus and Ro Cammarota on noviembre 19, 2024 at 12:00 am
Forensic analysis heavily relies on DNA analysis techniques, notably autosomal Single Nucleotide Polymorphisms (SNPs), to expedite the identification of unknown suspects through genomic database searches. Howe...
- Elevated expression of APOO as a potential prognostic marker in breast cancer: insights from bioinformatic analysis and experimental validationpor Yang Bai, Qian Tang, Liang Zheng, Jun He, Wenjian Wang, Liqi Li and Ju Yu on noviembre 18, 2024 at 12:00 am
Apolipoprotein O (APOO) has been identified through bioinformatic prediction analysis as being highly expressed in various tumors, including breast cancer (BRCA). However, further investigations are required t...
- Genome-wide association analysis of cystatin c and creatinine kidney function in Chinese womenpor Yang Cai, Hongyao Lv, Meng Yuan, Jiao Wang, Wenhui Wu, Xiaoyu Fang, Changying Chen, Jialing Mu, Fangyuan Liu, Xincheng Gu, Hankun Xie, Yu Liu, Haifeng Xu, Yao Fan, Chong Shen and Xiangyu Ma on noviembre 18, 2024 at 12:00 am
With increasing incidence and treatment costs, chronic kidney disease (CKD) has become an important public health problem in China, especially in females. However, the genetic determinants are very limited. Th...
- Hearing impairment and vestibular function in patients with a pathogenic splice variant in the LHX3 genepor Åsa Kjellgren, Elenor Lundgren, Irina Golovleva, Berit Kriström and Mimmi Werner on noviembre 15, 2024 at 12:00 am
LHX3 is a gene encoding a LIM-homeodomain transcription factor important for the fetal development of several organs, such as the pituitary gland, spinal motor neurons and the inner ear. Pathogenic and likely pat...