Most Recent Articles: Fluids and Barriers of the CNS Most Recent Articles: Fluids and Barriers of the CNS
- C9ORF72 patient-derived endothelial cells drive blood-brain barrier disruption and contribute to neurotoxicitypor Ana Aragón-González, Allan C Shaw, Jannigje R Kok, Florence S Roussel, Cleide dos Santos Souza, Sarah M Granger, Tatyana Vetter, Yolanda de Diego, Kathrin C Meyer, Selina N Beal, Pamela J Shaw and Laura Ferraiuolo el abril 11, 2024 a las 12:00 am
The blood-brain barrier (BBB) serves as a highly intricate and dynamic interface connecting the brain and the bloodstream, playing a vital role in maintaining brain homeostasis. BBB dysfunction has been associ...
- SARS-CoV-2 causes dysfunction in human iPSC-derived brain microvascular endothelial cells potentially by modulating the Wnt signaling pathwaypor Shigeru Yamada, Tadahiro Hashita, Shota Yanagida, Hiroyuki Sato, Yukuto Yasuhiko, Kaori Okabe, Takamasa Noda, Motohiro Nishida, Tamihide Matsunaga and Yasunari Kanda el abril 8, 2024 a las 12:00 am
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), which is associated with various neurological symptoms, including nausea, dizziness, headache, encephali...
- Fasting upregulates the monocarboxylate transporter MCT1 at the rat blood-brain barrier through PPAR δ activationpor Stéphanie Chasseigneaux, Véronique Cochois-Guégan, Lucas Lecorgne, Murielle Lochus, Sophie Nicolic, Corinne Blugeon, Laurent Jourdren, David Gomez-Zepeda, Stefan Tenzer, Sylvia Sanquer, Valérie Nivet-Antoine, Marie-Claude Menet, Jean-Louis Laplanche, Xavier Declèves, Salvatore Cisternino and Bruno Saubaméa el abril 8, 2024 a las 12:00 am
The blood-brain barrier (BBB) is pivotal for the maintenance of brain homeostasis and it strictly regulates the cerebral transport of a wide range of endogenous compounds and drugs. While fasting is increasing...
- Single-cell analysis of mesenchymal cells in permeable neural vasculature reveals novel diverse subpopulations of fibroblastspor William E. Bastedo, R. Wilder Scott, Martin Arostegui and T. Michael Underhill el abril 5, 2024 a las 12:00 am
In the choroid plexus and pituitary gland, vasculature is known to have a permeable, fenestrated phenotype which allows for the free passage of molecules in contrast to the blood brain barrier observed in the ...
- [1-11C]-Butanol Positron Emission Tomography reveals an impaired brain to nasal turbinates pathway in aging amyloid positive subjectspor Neel H. Mehta, Xiuyuan Wang, Samantha A. Keil, Ke Xi, Liangdong Zhou, Kevin Lee, Wanbin Tan, Edward Spector, Amirhossein Goldan, James Kelly, Nicolas A. Karakatsanis, P. David Mozley, Sadek Nehmeh, J. Levi Chazen, Simon Morin, John Babich… el abril 2, 2024 a las 12:00 am
Reduced clearance of cerebrospinal fluid (CSF) has been suggested as a pathological feature of Alzheimer’s disease (AD). With extensive documentation in non-human mammals and contradictory human neuroimaging d...